The twentieth century has seen a dramatic increase in human uses of and human impacts on water resources, increasing competition over water as well as depleting or deteriorating its availability. Given its importance to human life and livelihoods, water is becoming one of the major foci of environmental research. The coincidence of water scarcity with poverty in many parts of the world makes it a focal point of international development efforts. With engineering thinking dominating over past decades, water management research has embraced more integrative approaches triggered by an increasing awareness of failures that focused on narrow single issues or technical solutions to address the complex challenges of sustainable water management. This chapter explores whether, when, and how more inclusive framings might enable more socially relevant and impactful research, and lead to more effective action. Discussion begins by establishing what a frame is and then defining what is meant by an “inclusive frame” for interdisciplinary research on environmental problems. Seven frames in water research are examined; emphasis is given to how framings are driven by differences in normative and theoretical positions, which yields very different views on progress and how best to achieve it. Next, the use of more inclusive frames in academic or research contexts is explored using two examples which incorporate multiple normative and theoretical positions. Barriers encountered by academics and researchers, as they attempt to use inclusive frames, are then examined. To explore how inclusive frames can be used to address real-world problems, three cases highlight the possibilities and challenges in applying inclusive frames to research with the goal of informing action and practice.