While sacred groves (forest fragments protected for religious reasons) are widely acknowledged to have a beneficial effect on biodiversity conservation, the ecological benefits of individual sacred trees remain unknown. Fig trees are present as sacred trees in human dominated landscapes across South Asia and are considered keystone species for wildlife in tropical forests. If frugivores continue to visit fig trees in disturbed landscapes, they may deposit seeds of other tree species beneath fig canopies, ultimately facilitating forest regeneration. We studied whether sacred fig trees in Tamil Nadu, India can facilitate seed dispersal in human-dominated landscapes. We quantified abundance of sacred fig trees at the study site, assessed whether seed-dispersing frugivore visitation to fig trees is affected by human disturbance, and compared tree seedling density beneath fig trees and open areas. We found that some species of frugivorous birds and bats will visit large fig trees in conditions of high human disturbance and that tree seedling density is significantly higher under sacred trees compared to open areas. By promoting frugivore activity, sacred fig trees may have a beneficial effect on biodiversity conservation in human-dominated landscapes.