Deforestation is recognized as one of the most significant component in LULC and global changes scenario. It is imperative to assess its trend and the rates at which it is occurring. The changes will have long-lasting impact on regional climate and in turn on biodiversity. In North-East India, one of the recognized global biodiversity hotspots, approximately 30% of total forest cover is under pressure of rapid land use changes. This region harbors variety of rare and endemic species of flora and fauna. It also has a strong bearing on regional climatic conditions. Extensive shifting cultivation, compounded by increasing population pressure and demands for agriculture land are the prime drivers in addition to other proximate drivers of deforestation. It is therefore of prime concern to analyse forest cover changes in the region, assess rate of change and extent and to identify the areas, which show repetitive changes. We analyzed forest cover maps from six temporal datasets based on satellite data interpretation, converted to geospatial database since 1972 till 1999. The states of Meghalaya, Nagaland and Tripura show highest changes in forest cover. Arunachal Pradesh shows least dynamic areas and maintains a good forest cover owing to its topographical inaccessibility in some areas. The present study reports the forest cover changes in the region using geospatial analysis and analyse them to devise proper management strategies.